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Coronavirus disease 2019 (COVID-19) Resources for Clinicians: Research Journal Articles

This guide provides access to clinically oriented information for healthcare providers on Covid-19 and related healthcare issues. Resources that are subscription only will be designated with USA Only.

Selected articles on COVID-19

Assessment of protection against reinfection with SARS-CoV-2 among 4 million PCR-tested individuals in Denmark in 2020: a population-level observational study from The Lancet (Free), March 27, 2021

Discriminant Accuracy of the SOFA Score for Determining the Probable Mortality of Patients With COVID-19 Pneumonia Requiring Mechanical Ventilation (research letter) from JAMA (Free), February 17, 2021

Effect of a Single High Dose of Vitamin D3 on Hospital Length of Stay in Patients With Moderate to Severe COVID-19
A Randomized Clinical Trial
from JAMA (Free), February 17, 2021

Pregnancy, Postpartum Care, and COVID-19 Vaccination in 2021 (editorial comment) from JAMA (Free), February 8, 2021

COVID-19 Vaccination in Pregnant and Lactating Women (editorial comment) from JAMA (Free), February 8, 2021

Association of Smoking and Cumulative Pack-Year Exposure With COVID-19 Outcomes in the Cleveland Clinic COVID-19 Registry from JAMA Internal Medicine (Free, research letter), January 25, 2021

Association of Early-Phase In-Hospital Glycemic Fluctuation With Mortality in Adult Patients With Coronavirus Disease 2019 from Diabetes Care (Free), January 21, 2021

Prevalence and risk factors for delirium in critically ill patients with COVID-19 (COVID-D): a multicentre cohort study from The Lancet Respiratory Medicine (Free), January 8, 2021

SARS-CoV-2 Transmission From People Without COVID-19 Symptoms from JAMA Network Open (Free), January 7, 2021

Early High-Titer Plasma Therapy to Prevent Severe Covid-19 in Older Adults from The England Journal of Medicine (Free), January 6, 2021

COVID-19 severity impacts on long-term neurological manifestation after hospitalisation from MedRXiv (Free, preprint), January 2, 2021

Efficacy and Safety of the mRNA-1273 SARS-CoV-2 Vaccine from The New England Journal of Medicine (Free), December 30, 2020

Persistent symptoms 1.5–6 months after COVID-19 in non-hospitalised subjects: a population-based cohort study from Thorax (Free), December 3, 2020

Repurposed Antiviral Drugs for Covid-19 — Interim WHO Solidarity Trial Results from The New England Journal of Medicine (Free), December 2, 2020

Racial and Ethnic Disparities in COVID-19–Related Infections, Hospitalizations, and Deaths: A Systematic Review from Annals of Internal Medicine (Free), December 1, 2020

Myocardial Injury in Severe COVID-19 Compared to Non-COVID Acute Respiratory Distress Syndrome from Circulation (Free), November 13, 2020

SARS-CoV-2 Clinical Syndromes and Predictors of Disease Severity in Hospitalized Children and Youth from The Journal of Pediatrics (Free), November 10, 2020

Characterization of Myocardial Injury in Patients With COVID-19 from the Journal of the American College of Cardiology (Free), November 3, 2020

A Machine Learning Study of 534,023 Medicare Beneficiaries with COVID-19: Implications for Personalized Risk Prediction from medRxiv (Free), October 30, 2020 

Abdominal imaging findings in patients with SARS-CoV-2 infection: a scoping review from Abdominal Radiology (Free), November 6, 2020

Persistence of viral RNA, pneumocyte syncytia and thrombosis are hallmarks of advanced COVID-19 pathology from EBioMedicine (Free), November 3, 2020

Remdesivir for the Treatment of Covid-19 — Final Report from The New England Journal of Medicine (Free), October 8, 2020

Genomic evidence for reinfection with SARS-CoV-2: a case study from The Lancet Infectious Diseases (Free), October 12, 2020

Repurposed antiviral drugs for COVID-19; interim WHO SOLIDARITY trial results from medRxiv (Free), October 15, 2020

SARS-CoV-2 organising pneumonia: ‘Has there been a widespread failure to identify and treat this prevalent condition in COVID-19?’ from BMJ Open Respiratory Research (Free), September 5, 2020

Risk Factors for Hospitalization, Mechanical Ventilation, or Death Among 10,131 US Veterans With SARS-CoV-2 Infection from JAMA Network Open (Free), September 23, 2020

Association of Vitamin D Status and Other Clinical Characteristics With COVID-19 Test Results from JAMA Network Open (Free), September 3, 2020

Neuroinvasion of SARS-CoV-2 in human and mouse brain from bioRxiv (Free), September 8, 2020

COVID‐19 and pregnancy: A review of clinical characteristics, obstetric outcomes and vertical transmission from Aust N Z J Obstet Gynaecol (Free), August 10, 2020

A mechanistic model and therapeutic interventions for COVID-19 involving a RAS-mediated bradykinin storm from eLife (Free), July 7, 2020

Simply saliva: stability of SARS-CoV-2 detection negates the need for expensive collection devices from medRxiv (Free), August 4, 2020

Clinical Course and Molecular Viral Shedding Among Asymptomatic and Symptomatic Patients With SARS-CoV-2 Infection in a Community Treatment Center in the Republic of Korea from JAMA Internal Medicine (Free), August 6, 2020

Rapid Decay of Anti–SARS-CoV-2 Antibodies in Persons with Mild Covid-19 from the New England Journal of Medicine (Free), July 21, 2020

Outcomes of Cardiovascular Magnetic Resonance Imaging in Patients Recently Recovered From Coronavirus Disease 2019 (COVID-19) from JAMA Cardiology (Free), July 27, 2020

Association of Cardiac Infection With SARS-CoV-2 in Confirmed COVID-19 Autopsy Cases from JAMA Cardiology (Free), July 27, 2020

Association Between Universal Masking in a Health Care System and SARS-CoV-2 Positivity Among Health Care Workers from JAMA (Free), July 14, 2020

Coronavirus Disease 2019 Pandemic Measures: Reports From a National Survey of 9,120 ICU Clinicians from Critical Care Medicine (Free), July 2, 2020

Intrauterine Transmission of SARS-COV-2 Infection in a Preterm Infant from The Pediatric Infectious Disease Journal (Free), July 10, 2020.

Risk of Ischemic Stroke in Patients With Coronavirus Disease 2019 (COVID-19) vs Patients With Influenza from JAMA Neurology (Free), July 2, 2020

Effect of Colchicine vs Standard Care on Cardiac and Inflammatory Biomarkers and Clinical Outcomes in Patients Hospitalized With Coronavirus Disease 2019: The GRECCO-19 Randomized Clinical Trial from JAMA Network Open (Free), June 24, 2020

Genomewide Association Study of Severe Covid-19 with Respiratory Failure from the New England Journal of Medicine (Free), June 17, 2020

Prevalence and Impact of Myocardial Injury in Patients Hospitalized with COVID-19 Infection from Journal of the American College of Cardiology (Free), June 5, 2020

Approach to Acute Cardiovascular Complications in COVID-19 Infection from Circulation: Heart Failure (Free), June 5, 2020

Prevention, diagnosis and treatment of venous thromboembolism in patients with COVID-19: CHEST Guideline and Expert Panel Report (pre-print) from CHEST (Free), May 26, 2020

Nasal Gene Expression of Angiotensin-Converting Enzyme 2 in Children and Adults from JAMA (Free), May 20, 2020

The association between severe COVID‐19 and low platelet count: evidence from 31 observational studies involving 7613 participants from the British Journal of Haematology (Free), May 18, 2020

Respiratory Mechanics and Gas Exchange in COVID-19 Associated Respiratory Failure from Annals of the American Thoracic Society (Free), May 20, 2020

Acute heart failure in multisystem inflammatory syndrome in children (MIS-C) in the context of global SARS-CoV-2 pandemic from Circulation (Free), May 17, 2020

Remdesivir for the Treatment of Covid-19 — Preliminary Report from The New England Journal of Medicine (Free), May 22, 2020

Characterization and clinical course of 1000 patients with coronavirus disease 2019 in New York: retrospective case series from BMJ (Free), May 29, 2020

Use of Prone Positioning in Nonintubated Patients With COVID-19 and Hypoxemic Acute Respiratory Failure from JAMA (Free), May 15, 2020

Use of renin–angiotensin–aldosterone system inhibitors and risk of COVID-19 requiring admission to hospital: a case-population study from The Lancet (Free), May 14, 2020

Interpreting Diagnostic Tests for SARS-CoV-2 from JAMA (Free), May 6, 2020

Management of acute ischemic stroke in patients with COVID-19 infection: Report of an international panel from International Journal of Stroke (Free), May 3, 2020

Management of COVID-19 Respiratory Distress from JAMA (Free), April 24, 2020

Spike mutation pipeline reveals the emergence of a more transmissible form of SARS-CoV-2 (preprint) from bioRxiv (Free), April 30, 2020

Surviving Sepsis Campaign: Guidelines on the Management of Critically Ill Adults with Coronavirus Disease 2019 (COVID-19) from Critical Care Medicine (Free), March 27, 2020

Acute Acro-Ischemia in the Child at the Time of COVID-19 (case report) from The International Federation of Podiatrists (Free)

Awareness, Attitudes, and Actions Related to COVID-19 Among Adults With Chronic Conditions at the Onset of the U.S. Outbreak: A Cross-sectional Survey from Annals of Internal Medicine (Free), April 9, 2020

The Science Underlying COVID-19: Implications for the Cardiovascular System from Circulation (Free), April 15, 2020

Pharmacologic Treatments for Coronavirus Disease 2019 (COVID-19): A Review from JAMA (Free), April 13, 2020

Outcomes of hydroxychloroquine usage in United States veterans hospitalized with Covid-19 (preprint) from medRxiv (Free)

Chloroquine diphosphate in two different dosages as adjunctive therapy of hospitalized patients with severe respiratory syndrome in the context of coronavirus (SARS-CoV-2) infection: Preliminary safety results of a randomized, double-blinded, phase IIb clinical trial (CloroCovid-19 Study) (preprint) from medRxiv (Free), April 16, 2020

Compassionate Use of Remdesivir for Patients with Severe Covid-19 from The New England Journal of Medicine (Free), April 10, 2020

CSC Expert Consensus on Principles of Clinical Management of Patients with Severe Emergent Cardiovascular Diseases during the COVID-19 Epidemic from Circulation (Free), March 27, 2020.

COVID-19: Attacks the 1-Beta Chain of Hemoglobin and Captures the Porphyrin to Inhibit Human Heme Metabolism preprint from ChemRxiv (Free), April 9, 2020

Renin–Angiotensin–Aldosterone System Inhibitors in Patients with Covid-19 from The New England Journal of Medicine, March 30, 2020 (Free)

Effect of Noninvasive Ventilation Delivered by Helmet vs Face Mask on the Rate of Endotracheal Intubation in Patients With Acute Respiratory Distress Syndrome from JAMA,, June 14, 2016 (Free).  See the related NBC news article Texas 'mom and pop' business flooded with orders for helmet ventilators amid coronavirus crisis, March 31, 2020.

Presymptomatic Transmission of SARS-CoV-2 — Singapore, January 23–March 16, 2020 from the CDC, April 1, 2020 (Free)

The neuroinvasive potential of SARS‐CoV2 may play a role in the respiratory failure of COVID‐19 patients from the Journal of Medical Virology, February 27, 2020, revised March 17 (Free)

Covid-19 in Critically Ill Patients in the Seattle Region — Case Series from The New England Journal of Medicine, March 30, 2020 (Free)

Catheterization Laboratory Considerations During the Coronavirus (COVID-19) Pandemic: From ACC’s Interventional Council and SCAI (pre-proof) from The Journal of the American College of Cardiology, March 16, 2020 (Free)

Coronavirus disease 2019 (COVID-19): update for anesthesiologists and intensivists March 2020 from Anaesthesist, March 24, 2020 (Free)

Neonatal Early-Onset Infection With SARS-CoV-2 in 33 Neonates Born to Mothers With COVID-19 in Wuhan, China research letter from JAMA Pediatrics, March 26, 2020 (Free)

Training and Fit Testing of Health Care Personnel for Reusable Elastomeric Half-Mask Respirators Compared With Disposable N95 Respirators research letter from JAMA, March 25, 2020 (Free)

Characteristics and Outcomes of 21 Critically Ill Patients With COVID-19 in Washington State research letter from JAMA, March 19, 2020 (Free)

Impact of non-pharmaceutical interventions (NPIs) to reduce COVID19 mortality and healthcare demand from the Imperial College COVID-19 Response Team, March 16, 2020 (Free)

Too Many Patients. A Framework to Guide Statewide Allocation of Scarce Mechanical Ventilation During Disasters from Chest, April 2019 (USA only)

A Trial of Lopinavir–Ritonavir in Adults Hospitalized with Severe Covid-19 from The New England Journal of Medicine, March 18, 2020 (Free)

Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study from The Lancet, March 11, 2020 (Free)

Aerosol and Surface Stability of SARS-CoV-2 as Compared with SARS-CoV-1 (correspondence) from The New England Journal of Medicine, March 17, 2020 (Free)

Substantial undocumented infection facilitates the rapid dissemination of novel coronavirus (SARS-CoV2) from Science, March 16, 2020 (Free)

First Case of 2019 Novel Coronavirus in the United States from The New England Journal of Medicine, March 5, 2020 (Free)

Pulmonary Pathology of Early-Phase 2019 Novel Coronavirus (COVID-19) Pneumonia in Two Patients With Lung Cancer from Journal of Thoracic Oncology, in press (Free)

Severe COVID-19 Pneumonia: Assessing Inflammation Burden with Volume-rendered Chest CT from Images in Cardiothoracic Imaging, March 6, 2020 (Free)

Asymptomatic carrier state, acute respiratory disease, and pneumonia due to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2): Facts and myths from Journal of Microbiology, Immunology and Infection, March 4, 2020 (Free)

Clinical Characteristics of 138 Hospitalized Patients With 2019 Novel Coronavirus–Infected Pneumonia in Wuhan, China from JAMA, February 7, 2020 (Free)

Early Transmission Dynamics in Wuhan, China, of Novel Coronavirus–Infected Pneumonia from The New England Journal of Medicine, January 29, 2020 (Free)

The Lancet

COVID-19 Resource Center (Free): To assist health workers and researchers working under challenging conditions to bring this outbreak to a close, The Lancet has created a Coronavirus Resource Centre. This resource brings together new 2019 novel coronavirus disease (COVID-19) content from across The Lancet journals as it is published. All of our COVID-19 content is free to access.

 

Springer Nature

SARS CoV-2 and COVID-19 (Free): SARS-CoV-2 is a new virus responsible for an outbreak of respiratory illness known as COVID-19, which has spread to several countries around the world. As a leading research publisher, Springer Nature is committed to supporting the global response to emerging outbreaks by enabling fast and direct access to the latest available research, evidence, and data.

BMJ

Coronavirus (covid-19): Latest news and resources (Free): This page collects all BMJ coverage of the coronavirus outbreak from across the BMJ's journals and learning resources. All articles and resources are freely available.

Cochrane Special Collections

Coronavirus (COVID-19): evidence relevant to critical care (Free): This Special Collection focuses on evidence relevant to critical care.

Coronavirus (COVID-19): infection control and prevention measures (Free): This Special Collection focuses on infection control and prevention measures. 

Academia.edu

 Covid-19 (Coronavirus) (Free):  highlights key research papers and lists related readings to those papers based on an algorithm, from Academia.edu

Mary Ann Liebert, Inc.

Coronavirus Resource Center Archive (Free): To support the continued growth and rapid development of research around the world during the COVID-19 pandemic, Mary Ann Liebert, Inc. publishers have collected all of their relevant academic resources to inform and provide opportunities within the fields of coronavirus research, viral immunology, telemedicine, and public health crises. All articles are available freely online.

Cell Press

Cell Press Coronavirus Resource Hub (Free): At Cell Press, we recognize the urgent need to quickly share information about SARS-CoV-2 (also referred to as 2019-nCoV), the coronavirus that causes COVID-19. On this hub page, curated by members of our editorial team, you'll find our policies for submitting papers related to COVID-19, as well as content about the outbreak as it appears in Cell Press journals.

Wiley Online Library

COVID-19 Novel Coronavirus (Free): As a publisher of trusted health science, we’ve made the relevant research articles, book chapters and entries in our major references freely available, in support of the global efforts in diagnosis, treatment, prevention and further research in this disease and similar viral respiratory infections. 

American Society for Microbiology

LitCovid

LitCovid (Free): LitCovid is a curated literature hub for tracking up-to-date scientific information about the 2019 novel Coronavirus. It is the most comprehensive resource on the subject, providing a central access to 1200 (and growing) research articles in PubMed. The articles are updated daily and are further categorized by different research topics and geographic locations for improved access. 

PubMed Central COVID-19 Articles

PubMed Central COVID-19 articles (Free):  On March 13, 2020, the National Science and Technology Advisors from a dozen countries, including the United States, called on publishers to voluntarily agree to make their COVID-19 and coronavirus-related publications, and the available data supporting them, immediately accessible in PubMed Central (PMC) and other appropriate public repositories to support the ongoing public health emergency response efforts.

Elsevier Coronavirus Research Repository

Coronavirus Research Respository (Free): Welcome to the Elsevier Coronavirus Research Repository, presenting scholarly articles on COVID-19, SARS, MERS and other coronaviruses research.

The New England Journal of Medicine

Coronavirus (COVID-19) (Free): A collection of articles and other resources on the Coronavirus (Covid-19) outbreak, including clinical reports, management guidelines, and commentary.

Ovid

COVID-19 Tools and Resources for Clinicians (Free): COVID-19 resources for front-line clinicians and medical researchers are available in response to the outbreak of coronavirus that began in the Chinese city of Wuhan with infections now confirmed in numerous other countries.

medRxiv

COVID-19 SARS-CoV-2 preprints from medRxiv and bioRxiv (Free):  medRxiv is a preprint server for the health sciences.  Preprints are preliminary reports of work that have not been certified by peer review. Per their disclaimer, preprints should not be relied on to guide clinical practice or health-related behavior and should not be reported in news media as established information.

JAMA

Coronavirus Disease 2019 (COVID-19) (Free): Browse the JAMA Network COVID-19 collection, including Q&A's with NIAID's Anthony Fauci and past publications on vaccine development, infection control, and public health preparedness.

American College of Radiology

ACR COVID-19 Clinical Resources for Radiologists (Free): To help radiology professionals make more informed decisions during the Coronavirus (COVID-19) pandemic, the ACR has collected radiology-specific materials. The ACR will update this page regularly, as reliable information becomes available.  The resources below are not intended to be — nor offered as — comprehensive medical guidelines, but may be of help as the radiological community works to protect patients and health care providers from this virus.